Mind the gap! The seduction of the synapse
[2007 Public Library of Science (open access)]
Bah! All that talk about brain cells and grey matter! Let’s focus on where the real interesting action is inside your head: the connections between your brain cells—synapses. From the ancient past to the frenzied future—it's all about making connections.
Guests
- Seth Grant
- Professor of Molecular Neuroscience Director, Genes to Cognition Program (G2C) Edinburgh University Wellcome Trust Sanger Institute, Cambridge University
- Geoffrey Goodhill
- Professor, Computational Neuroscience Queensland Brain Institute and School of Mathematical and Physical Sciences University of Queensland.
- Huda Akil
- Co-director and Research Professor Professor of Neurosciences Distinguished University Professor and Quarton The Molecular and Behavioural Neuroscience Institute Department of Psychiatry University of Michigan USA
Further Information
- All in the Mind blog with Natasha Mitchell
- Look out for occasional extra audio and program information on the All in the Mind blog
- Molecules to Mind: Challenges for the 21st Century
- Session at the AAAS Conference 2011, Washington DC
- The Blue Brain Project
- The Blue Brain Project is "reconstructing the brain piece by piece and building a virtual brain in a supercomputer".
- From the connectome to the synaptome: an epic love story
- Javier DeFelipe, Science Nov 26, 2010;330(6008):1198-201.
- The early history of the synapse: from Plato to Sherrington
- Max Bennett; Brain Research Bulletin, 1999 Sep 15;50(2):95-118.
- The origin and evolution of synapses
- Tomas J. Ryan and Seth G.N Grant. Nat Rev Neurosci. 2009 Oct;10(10):701-12.
- A general basis for cognition in the evolution of synapse signalling complexes
- Seth Grant, Cold Spring Harb Symp Quant Biol. 2009;74:249-57.
- Computing behaviour in complex synapses
- Seth Grant, The Biochemist, Volume 32 No 2 April 2010
- Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks
- Marcelo P. Coba, Andrew J. Pocklington, Mark O. Collins, Maksym V. Kopanitsa, Rachel T. Uren, Sajani Swamy, Mike D. R. Croning, Jyoti S. Choudhary, and Seth G. N. Grant, Sci. Signal., 28 April 2009 Vol. 2, Issue 68, p. ra19
- Challenges and Opportunities in Mining Neuroscience Data
- Huda Akil, Maryann E. Martone, David C. Van Essen; Science 331, 708 (2011)l. (PDF file).
- Theoretical Models of Neural Development
- Hugh D. Simpson, Duncan Mortimer, and Geoffrey J. Goodhill, Current Topics in Development Biology, 87, 1-51, 2009.
- A simple model can unify a broad range of phenomena in retinotectal map development
- Simpson, H.D. & Goodhill, G.J. (2011). Biological Cybernetics, 104, 9-29 (PDF file).
Credits
- Producer
- Natasha Mitchell / Maria Tickle
- Presenter
- Natasha Mitchell
Tuesday, December 06, 2011
All in the Mind - Mind the gap! The seduction of the synapse
In this episode of All in the Mind, Natasha Mitchell speaks with several neuroscientists about synapses, the tiny gaps between brain neurons.
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